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New, revolutionary de novo assembly algorithm
Click to enlarge.CLC bio’s new de novo assembly algorithm will change the standards of de novo assembly of large genomes by enabling de novo assembly of gigabase-size genomes on a single desktop computer in a reasonable amount of time.
Visit clcdenovo.com for more detail on our de novo assembler
Video interviews with customers on de novo assembly – see for yourself!
Single read:
| Comparison of ABySS and CLC bio’s de novo assembly on an Illumina Genome Analyzer dataset consisting of approximately 3.6 billion reads resulting in 38 fold coverage of the human genome and a total dataset size of approximately 130 Giga bases in total | ||
| CLC bio | ABySS | |
| Number of computers | 1 | 21 |
| Time spent (hours) | 6 | 15 |
| Total RAM needed (GB) | 21 | 336 |
| Contigs >= 1000 bp | ||
| - Number of contigs | 638.661 | 549,522 |
| - Mean size (bp) | 1,918 | 1,703 |
| - Max size (bp) | 18,222 | 15,911 |
| - N50 size (bp) | 2,021 | 1,731 |
| - Sum (Gbp) | 1.2 | 0.9 |
Paired-end reads:
| Comparison of ABySS and CLC bio’s de novo assembly on an Illumina Genome Analyzer dataset consisting of approximately 3.6 billion reads resulting in 38 fold coverage of the human genome and a total dataset size of approximately 130 Giga bases in total | ||
| CLC bio | ABySS | |
| Number of computers | 1 | 21 |
| Time spent (hours) | 7 | 80 |
| Total RAM needed (GB) | 42 | 336 |
| Contigs >= 1000 bp | ||
| - Number of contigs | 655,413 | 680,230 |
| - Mean size (bp) | 2,090 | 2,093 |
| - Max size (bp) | 32,285 | 18,800 |
| - N50 size (bp) | 2,273 | 2,282 |
| - Sum (Gbp) | 1.4 | 1.4 |
Details of the benchmarks are described in our white paper on the new de novo assembler.
